Research-backed supplements that may help manage symptoms and promote overall well-being after during and immediately following nicotine cessation.

The following recommendations are not only supported by the clinical literature but also informed by our positive experiences working with people recovering from nicotine dependencies. Unique product links and specific brands are frequently updated for the best quality, pricing and availability. Each item is a trusted brand we endorse.

Check with your healthcare provider before starting any herbal or nutritional supplements


L-Tyrosine, an amino acid, provides support for mental clarity and mood regulation.

Nicotine withdrawal can lead to cognitive challenges and fluctuations in mood. L-Tyrosine is a precursor to dopamine, a neurotransmitter responsible for feelings of pleasure and well-being. By incorporating L-Tyrosine supplementation, someone may experience improved mental focus and heightened motivation.

Its ability to support mood regulation complements its cognitive benefits. By promoting a stable mood, L-Tyrosine can help people better cope with emotional challenges that may arise during nicotine withdrawal.

RECOMMENDED DOSE: 750 – 3000 mg per day in divided doses

How It Helps

  • Supports mental clarity and focus during nicotine withdrawal
  • Acts as a precursor to dopamine for enhanced motivation
  • Regulates mood to cope with emotional challenges
  • Note: Consult with a healthcare professional before considering L-Tyrosine supplementation, especially if you have specific health conditions or are taking other medications.

Vitamin c

Vitamin C, an essential cofactor, plays a key role in cognitive benefits during nicotine withdrawal, including improving concentration and memory.

Its involvement as a cofactor in various enzymatic reactions is crucial for the synthesis of neurotransmitters like dopamine and norepinephrine, which are needed for cognitive function and emotional well-being.

RECOMMENDED DOSE: 500 – 2000 mg per day in divided doses

How it Helps

  • Acts as a cofactor for cognitive benefits
  • Supports the synthesis of neurotransmitters
  • Combats oxidative stress for brain health


B-Complex vitamins provide essential support for the nervous system, improving the well-known symptoms of irritability, anxiety, and difficulty sleeping.

B-vitamins, including B1 (thiamine), B2 (riboflavin), B3 (niacin), B5 (pantothenic acid), B6 (pyridoxine), B7 (biotin), B9 (folate), and B12 (cobalamin), play roles in supporting nerve health, energy metabolism, and the production of neurotransmitters.

Additionally, B-Complex vitamins work synergistically, each contributing to different aspects of nervous system function and overall well-being. Their combined effects promote emotional stability, which is helpful during the emotional rollercoaster of nicotine withdrawal.

AMOUNT : 1 – 3 tablets per day

How It Helps

  • Supports the nervous system during withdrawal
  • Enhances energy metabolism and neurotransmitter production
  • Promotes emotional stability and balanced mood


5-HTP, a natural precursor to serotonin, could offer support for emotional well-being during nicotine withdrawal (mood swings, irritability, and depressive symptoms).

The amino acid is converted into serotonin in the brain, a neurotransmitter that plays a key role in regulating mood and promoting feelings of well-being. 

Additionally, 5-HTP supports healthy sleep patterns, which can be disrupted during nicotine withdrawal. By promoting restful sleep, it helps fight sleep disturbances and contributes to overall emotional health.

Note: 5-HTP should not be taken in combination with prescription anti-depressants or other medications that affect serotonin levels. Consult with a healthcare professional before considering 5-HTP supplementation, especially if you have specific health conditions or are taking other medications.

Amount : 200 – 400 mg per day in divided doses

How it Helps

  • Supports emotional well-being and mood balance
  • Promotes restful sleep during withdrawal
  • Aids in combating mood swings and anxiety

Magnesium Glycinate

Magnesium Glycinate can help offset the heightened stress, anxiety, and muscle tension.

Its  an essential mineral that plays a crucial role in promoting relaxation and supporting a healthy nervous system. Magnesium Glycinate, in particular, is a highly bioavailable form, that provides a gentle and calming effect, helping to ease nervousness and reduce muscle tension that may be present during withdrawal.

Also, magnesium supports sleep quality, which is often disrupted during nicotine withdrawal. By helping naturally regulate melatonin, the hormone responsible for sleep-wake cycles, Magnesium Glycinate promotes restful sleep, allowing people to experience better sleep during a time where it’s often hard to come by.

RECOMMENDED DOSE: 200-400 mg per day

How it Helps

  • Calms the nervous system and reduces feelings of anxiety
  • Promotes muscle relaxation and alleviates tension
  • Supports improved sleep quality and patterns

Vitamin e

Vitamin E offers crucial cellular protection and antioxidant support during nicotine withdrawal.

Nicotine withdrawal can lead to increased oxidative stress, causing damage to cells and tissues. Vitamin E is a powerful antioxidant that helps neutralize harmful free radicals and protect cells from oxidative damage. 

Amount : Follow dosing recommendations on package label

How it Helps

  • Provides cellular protection and antioxidant support
  • Enhances immune function during withdrawal
  • Supports skin health and may alleviate skin irritations

Vitamin D

Nicotine withdrawal can lead to fluctuations in mood, and Vitamin D plays a role in regulating mood and promoting a positive outlook. Adequate Vitamin D levels are associated with better emotional well-being and may help lessen feelings of sadness or anxiety that can creep up during withdrawal.

Vitamin D could be considered an essential supplement for people looking for mood support, emotional balance, and bone health during nicotine withdrawal, empowering them to navigate those rough first few weeks with greater emotional and physical resilience.

Amount : Doses vary

How it Helps

  • Provides mood support and promotes emotional balance
  • Supports bone health and maintains strong bones
  • Helps alleviate feelings of sadness or anxiety during withdrawal

Eleuthro root

Eleuthero Root, also known as Siberian Ginseng, is an adaptogenic herb that helps the body adapt to stress and supports overall energy levels.

Additionally, Eleuthero Root has been traditionally used to enhance stamina, endurance,  and energy which can be helpful during this period of transition. 

RECOMMENDED DOSE: Follow dosing instructions on package label

How It Helps

  • Combats fatigue and boosts energy levels
  • Enhances mental clarity and cognitive function
  • Supports immune function during recovery
  • Aids in reducing stress and promoting resilience


GABA, or Gamma-Aminobutyric Acid, offers calming support during the anxiety and restlessness of nicotine withdrawal.

GABA is an essential neurotransmitter that plays a vital role in promoting relaxation and reducing anxiety. By enhancing GABA levels, someone may experience a sense of calmness and reduced stress, making the withdrawal process more manageable.

Also, GABA’s calming effects can help lessen sleep disturbances commonly experienced during the first few weeks or months. By supporting healthy sleep patterns, GABA lets people get the rest they need for a smoother transition.

Amount : 1000 – 2000 mg per day in divided doses

How it Helps

  • Provides calming support and reduces anxiety
  • Supports healthy sleep patterns during withdrawal
  • Enhances overall tranquility and well-being

Passion flower

Passion Flower is a natural relaxation aid that offers calming support during nicotine withdrawal – specifically the restlessness and irritability.

It’s known for its soothing properties, which help reduce nervous tension and promote relaxation. By supporting a calm and tranquil state, Passion Flower can lessen the emotional strain in the early days and weeks.

Also, Passion Flower has been used to improve sleep quality, making it a valuable for those experiencing sleep disturbances. By improving sleep patterns, Passion Flower might help people rest more effectively and recharge their energy.

RECOMMENDED DOSE: 1000 – 2000 mg per day in divided doses

How It Helps

  • Eases feelings of anxiety and restlessness
  • Improves sleep quality and supports better rest
  • Non-addictive and safe for long-term use
  • Aids in managing stress during withdrawal

Contact Us

We’re here for you every step of the way towards a healthier and more fulfilling life. Contact us today for personalized guidance, support, and to learn more about our services. 

Please note: Dosage, frequency, duration, and combination recommendations of all listed products vary considerably depending upon your unique situation and needs. Check with your healthcare provider before starting any herbal or nutritional supplements, as they may interact with medications or exacerbate certain disease states.

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