Research-backed supplements that may help manage symptoms and promote overall well-being during detox and withdrawal from stimulants like cocaine, crack, amphetamine, and methamphetamine.

The following recommendations are not only supported by science but also informed by our positive experiences working with hundreds of people recovering from chemical dependencies. Unique product links and specific brands are frequently updated for the best quality, pricing and availability. Each item is a trusted brand we endorse.

Check with your healthcare provider before starting any herbal or nutritional supplements


L-Tyrosine is an amino acid that serves as a precursor for important neurotransmitters in the brain, including dopamine, norepinephrine, and epinephrine. During stimulant detox and withdrawal, the brain’s natural production of these neurotransmitters may be affected.

Stimulant use can deplete dopamine levels, leading to feelings of low mood and lethargy. L-Tyrosine is involved in the synthesis of dopamine, which plays a crucial role in motivation, pleasure, and reward.

Additionally, norepinephrine and epinephrine are important neurotransmitters that play a role in stress response and alertness. During stimulant withdrawal, people may experience fatigue and difficulty concentrating. L-Tyrosine can support the production of these neurotransmitters, potentially helping to increase alertness and focus.

RECOMMENDED DOSE: 750 – 3000 mg per day in divided doses

How It Helps

  • Supports mood and emotional well-being
  • Provides building blocks for dopamine production
  • Helps increase alertness and focus
  • Aids in balancing brain chemistry during stimulant withdrawal
  • Note: Consult with a healthcare professional before considering L-Tyrosine supplementation, especially if you have specific health conditions or are taking other medications.

Vitamin c

Vitamin C offers a cognitive boost and mood support during stimulant withdrawal.

Stimulant withdrawal can lead to cognitive fatigue and mood imbalances. Vitamin C, as a powerful antioxidant, supports brain health and cognitive function. By aiding in neurotransmitter synthesis, it helps improve mental clarity and cognitive performance.

Additionally, Vitamin C’s antioxidant properties combat oxidative stress, which can positively impact mood during the withdrawal process. By promoting a more balanced mood, it contributes to emotional stability.

Vitamin C is a valuable supplement for people seeking cognitive support and mood balance during stimulant withdrawal, enhancing overall mental well-being and resilience.

RECOMMENDED DOSE: 500 – 2000 mg per day in divided doses

How it Helps

  • Supports the immune system and enhances immune function
  • Combats oxidative stress and reduces inflammation
  • Supports mood regulation and emotional well-being
  • Provides essential antioxidant support during stimulant withdrawal


B-complex vitamins, a group of essential water-soluble nutrients, are crucial for maintaining energy levels and supporting the health of the nervous system.

During stimulant detox and withdrawal, the body’s energy reserves may be depleted, and the nervous system can become imbalanced. B complex supplementation can help provide the necessary support.

Additionally, B vitamins are involved in mood regulation and cognitive function. By supporting the production of neurotransmitters, such as serotonin and dopamine, B-complex supplementation may help manage mood swings and promote mental clarity.

AMOUNT : 1 – 3 tablets per day

How It Helps

  • Supports energy production and reduces fatigue
  • Promotes proper nerve function and nervous system health
  • Aids in calming the nervous system and reducing anxiety
  • Supports mood regulation and cognitive function


Rhodiola, an adaptogenic herb, has long been used to combat stress, promote mental clarity, and support overall well-being. 

Stimulant use can disrupt the body’s stress response system, leading to increased cortisol levels and feelings of anxiety. Rhodiola’s adaptogenic properties can help regulate the stress response, reducing cortisol levels and promoting a sense of calmness.

Additionally, rhodiola’s ability to combat fatigue and improve stamina can be helpful for those experiencing energy fluctuations during withdrawal.

Amount : 200 mg per day

How it Helps

  • Regulates the stress response and reduces anxiety
  • Enhances cognitive function and mental clarity
  • Provides an energy boost without stimulant effects
  • Supports overall well-being during stimulant withdrawal

Magnesium Glycinate

Magnesium glycinate is a highly absorbable form of magnesium known for its calming effects on the nervous system and its ability to promote muscle relaxation. 

Stimulant use can deplete magnesium levels in the body, which may lead to feelings of anxiety, restlessness, and muscle cramps. Supplementing with magnesium glycinate can help replenish these essential levels and support a more balanced nervous system response.

Additionally, magnesium plays a key role in supporting sleep quality, which can be disrupted during stimulant withdrawal. By promoting relaxation and easing muscle tension, magnesium glycinate may contribute to improved sleep patterns.

RECOMMENDED DOSE: 200-400 mg per day

How it Helps

  • Calms the nervous system and reduces feelings of anxiety
  • Promotes muscle relaxation and alleviates tension
  • Helps replenish depleted magnesium levels during stimulant withdrawal
  • Supports improved sleep quality and patterns


Omega-3 fatty acids, including EPA and DHA, are essential nutrients known for their numerous health benefits, especially for brain health and inflammation management.

Stimulant use can also disrupt the body’s inflammatory response and lead to oxidative damage. Omega-3 fatty acids have powerful anti-inflammatory properties that can help reduce inflammation and promote overall health.

Additionally, omega-3s are essential components of cell membranes in the brain, contributing to its structural integrity and cognitive function. Supplementing with omega-3s may support brain health, improve memory, and enhance mental clarity during withdrawal. 

Amount : Recommended between 2000 – 3000 mg total EPA/DHA

How it Helps

  • Supports brain health and cognitive function
  • Reduces inflammation in the body
  • Potential mood improvement and decreased symptoms of depression


L-Phenylalanine is an essential amino acid that serves as a precursor to dopamine, a neurotransmitter associated with mood and pleasure.

Stimulant use can deplete dopamine levels, leading to feelings of low mood and lack of pleasure. L-Phenylalanine acts as a building block for dopamine production, supporting mood enhancement and emotional well-being during withdrawal.

Also, L-Phenylalanine plays a role in other neurotransmitter synthesis, including norepinephrine and epinephrine, which are involved in stress response and energy regulation.

Amount : 500 – 2000 mg per day in divided doses

How it Helps

  • Supports mood enhancement and emotional well-being
  • Aids in dopamine synthesis and pleasure regulation
  • Promotes stress management and mental clarity
  • Contributes to positive emotions and social bonding

Eleuthro root

Eleuthero Root, also known as Siberian Ginseng, is a time-tested adaptogenic herb that combats fatigue, boosts energy levels, and promotes overall resilience. This could be considered as alternative to Rhodiola Rosea.

Stimulant use can lead to exhaustion and decreased energy levels. Eleuthero Root’s adaptogenic properties help the body adapt to stress, reducing fatigue and improving vitality.

Additionally, Eleuthero Root enhances mental clarity and cognitive function, supporting people in coping with cognitive challenges often experienced during the first few months up to a year following abstinence.

RECOMMENDED DOSE: Follow dosing instructions on package label

How It Helps

  • Combats fatigue and boosts energy levels
  • Enhances mental clarity and cognitive function
  • Supports immune function during recovery
  • Aids in reducing stress and promoting resilience
  • Note: We recommend only taking one adaptogenic herb at a time


L-Glutamine is an amino acid that plays a vital role in supporting gut health and managing cravings during stimulant detox and withdrawal.

It aids in managing cravings, especially for sugar and carbohydrates, which are common during withdrawal. By providing an alternative source of energy, it may help reduce the intensity of cravings.

Amount : 1000 – 3000 mg per day in divided doses

How it Helps

  • Supports cravings management during recovery
  • Promotes the production of neurotransmitters involved in regulating cravings
  • Helps stabilize blood sugar levels and curb cravings for sugary foods
  • Supports gut health and immune function

Passion flower

Passion Flower is a gentle and natural herb used to ease anxiety and restlessness during stimulant detox and withdrawal.

Stimulant use can lead to increased anxiety and disrupt the body’s stress response. Passion Flower’s calming properties soothe the nervous system, promoting a sense of calmness.

Additionally, it improves sleep quality, which is beneficial during withdrawal when sleep disturbances are common. Passion Flower offers a safe and non-addictive way to manage anxiety and promote relaxation without impairing cognitive function.

RECOMMENDED DOSE: 1000 – 2000 mg per day in divided doses

How It Helps

  • Eases feelings of anxiety and restlessness
  • Improves sleep quality and supports better rest
  • Non-addictive and safe for long-term use
  • Aids in managing stress during withdrawal

Contact Us

We’re here for you every step of the way towards a healthier and more fulfilling life. Contact us today for personalized guidance, support, and to learn more about our services. 

Please note: Dosage, frequency, duration, and combination recommendations of all listed products vary considerably depending upon your unique situation and needs. Check with your healthcare provider before starting any herbal or nutritional supplements, as they may interact with medications or exacerbate certain disease states.

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